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Rapid screening tool to detect early-stage diabetes
New device with potential to improve diabetes care and management for millions of patients Problem The CDC estimates that approximately 7 million people in US have diabetes and don't know it.1 Delayed diagnosis increases the risk of serious complications such as premature heart disease, stroke, and kidney failure.2 Accurate screening tools that fit...
Published: 2/3/2021
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Inventor(s): Yuebing Zheng, Kumar Sharma, Yaoran Liu, Zilong Wu
Keywords(s): Biomarkers, Chemical analysis, Diabetes, Diagnostics, Instrumentation, Photonics, Point-of-care, Renal
Category(s): Life sciences > Diagnostic
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Deep learning for rapid and robust fluorescence lifetime imaging
Deep-learning approach has the potential to unlock fluorescent lifetime imaging for clinical applications. Fluorescence lifetime imaging microscopy (FLIM) is a widely used tool for biomedical imaging that offers many unique advantages over typical intensity-based fluorescence microscopy. FLIM is advancing fundamental biological research by enabling...
Published: 1/25/2021
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Inventor(s): Hsin-Chih (Tim) Yeh, Yuan-I Chen, Yin-Jui Chang, Shih-Chu Liao, Trung Nguyen, Soonwoo Hong, Yu-An Kuo, Hsin-Chin Li
Keywords(s): Artificial intelligence (AI), Cancer, Diagnostics, Imaging, Machine learning, Medical imaging, Microscopy
Category(s): Life sciences > Diagnostic, Life sciences > Imaging > Microscopy
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Early detection of cancer from blood draw
Problem Eight million people die from cancer each year, and 90% of these deaths happen in cases where the cancer has spread throughout the body from the initial tumor site.1 In the early stages of cancer, tumor cells can shed from the primary mass and enter the bloodstream. Clinicians can glean important information about the tumor from these circulating...
Published: 1/13/2021
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Inventor(s): Livia Eberlin, Ruth Katz, Alena Bensussan, Tanweer Zaidi
Keywords(s): Cancer, Diagnostics, Mass spectrometry
Category(s): Life sciences > Medical devices, Life sciences > Diagnostic
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Sensitivity enhancement for diagnostic assays
ProblemThe COVID-19 pandemic has ushered in a new era of diagnostic testing. Patients now demand rapid results, and they want testing to happen in a safe and convenient setting. Regulatory agencies and the biotech industry are working together to meet this need. Fierce competition is emerging among the hundreds of tests that have now received Emergency...
Published: 12/17/2020
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Inventor(s): Yuebing Zheng, Youngsun Kim
Keywords(s): COVID-19, Diagnostics
Category(s): Life sciences > Diagnostic
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Br512: an improved DNA polymerase for isothermal amplification assays
Unmet needLoop-mediated isothermal amplification (LAMP) is a technique that allows for nucleic acid amplification without the need for a thermocycler. This technology enables testing for infections practically anywhere. Testing shortages have exacerbated the COVID-19 pandemic, and there is a high demand for tests that can provide rapid results outside...
Published: 12/11/2020
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Inventor(s): Andrew Ellington, Andre Maranhao, Sanchita Bhadra
Keywords(s): COVID-19, Diagnostics, Engineered enzyme, Isothermal amplification, LAMP, Nucleic acid amplification, Point-of-care, Point-of-need, Polymerase
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Research tools > Reagent, Life sciences > Synthetic biology, Life sciences > Diagnostic
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